Medigus - MUSE™ SYSTEM

About MUSE™


The MUSE system is a comprehensive device that enables an incisionless treatment procedure for persistent GERD.  The system allows physicians or gastroenterologists to perform fundoplication (the procedure which wraps the upper part of the stomach, or fundus, around the lower part of the esophagus) endoscopically instead of laparoscopically. The procedure conducted with the MUSE system may provide long-term, possibly permanent relief from GERD symptoms. MUSE addresses the root cause of the disorder, and therefore results in improved quality of life for people who suffer from reflux. Because endoscopic procedures do not require incisions, MUSE may be the preferred option for many patients.

Medigus, a pioneer in transforming existing open and laparoscopic surgical procedures into endoluminal (natural orifice) procedures developed the innovative MUSE system — combining a surgical stapler, ultrasonic sights for accurate positioning and a miniaturized video camera, all in a single instrument.

The MUSE procedure is a revolutionary, incisionless option in the treatment of GERD, that allows physicians to perform reconstruction of the esophageal valve through the mouth, eliminating the need for full-scale surgery in eligible GERD patients.

MUSE leverages the latest technological advancements to deliver a less-invasive and more patient-friendly alternative to laparoscopic fundoplication procedures.  The procedure is uniquely comprehensive, offering several advantages over current therapies.

See the how procedures using the MUSE system are conducted: MUSE system - see how it works

Who is eligible for the MUSE procedure?

Those who are 18 years or older, have been diagnosed with GERD by a physician, experience symptoms such as heartburn two or more times a week, and have been using PPIs 2-3 times a week for at least 6 months with some symptom relief, may benefit from being treated with MUSE system.

How effective is the MUSE procedure?

In a clinical study, 73% of patients who were treated with MUSE reported significant improvement in quality of life following the procedure. Of the total treatment group, 65%  eliminated use of any reflux medication and another 20% significantly reduced their need for medications.*

What does the procedure involve?

The procedure is performed under general anesthesia.  The MUSE system is administered transorally (through the mouth), so there are no incisions, which can mean reduced post-procedure recovery time. 

The procedure generally takes 60-90 minutes.  Afterwards, the patient is temporarily placed on a diet of liquids and soft foods, and then gradually returns to a normal diet.   Patients are able to resume normal daily activities within a few days post-procedure.

Who will perform my procedure? 

MUSE can only be used by gastroenterologists or surgeons who have been specifically trained.  Contact us to find a trained MUSE physician closest to you

Does the procedure hurt? 

As the procedure is performed under general anesthesia, precautions are taken to ensure patient comfort. Following the procedure, some patients have reported sore throat and minor pain in their abdomen.  These symptoms usually subside within a few days.

What can be expected post-procedure?

Following the procedure, patients are temporarily placed on a diet of liquids and soft foods, then gradually returned to a normal diet.   Patients are able to resume normal daily activities within a few days post-procedure.

* Zacherl et al,  Endoscopic anterior fundoplication with the Medigus Ultrasonic Surgical Endostapler (MUSE™) for gastroesophageal reflux disease: 6-month results from a multi-center prospective trial. Surgical Endoscopy, 2014.

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